Read Sharp MX-M266N / MX-M316N / MX-M356N (serv.man145) Regulatory Data online
MATERIAL SAFETY DATA SHEET
Page : 4/5
Date Issued : Oct. 8, 2014
MSDS No. F-02531
11.TOXICOLOGICAL INFORMATION
Acute Toxicity
Ingestion(oral)
: LD
50
> 2000mg/kg (Rats)
Inhalation
: LC
50
> 5.0mg/L (Rats)
Eye irritation
: Not an irritant (Rabbits)
Skin irritation
: Not an irritant (Rabbits)
Skin sensitizer
: No sensitization
Mutagenicity
: Negative (Ames Test)
Carcinogenicity : In 1996 the IARC reevaluated carbon black as a Group 2B carcinogen (possible human
carcinogen). This classification is given to chemicals for which there is inadequate human
evidence, but sufficient animal evidence on which to base an opinion of carcinogenicity. The
classification is based upon the development of lung tumors in rats receiving chronic inhalation
exposures to free carbon black at levels that induce particle overload of the lung. Studies
performed in animal models other than rats did not show any association between carbon black
and lung tumors. Moreover, a two-year cancer bioassay using a typical toner preparation, where
carbon black is bound in a resin matrix, demonstrated no association between toner exposure
and tumor development in rats.
evidence, but sufficient animal evidence on which to base an opinion of carcinogenicity. The
classification is based upon the development of lung tumors in rats receiving chronic inhalation
exposures to free carbon black at levels that induce particle overload of the lung. Studies
performed in animal models other than rats did not show any association between carbon black
and lung tumors. Moreover, a two-year cancer bioassay using a typical toner preparation, where
carbon black is bound in a resin matrix, demonstrated no association between toner exposure
and tumor development in rats.
Chronic Effect
: In a study in rats of chronic inhalation exposure to a typical toner, a mild to moderate degree of
lung fibrosis was observed in 92% of the rats in the high concentration (16mg/m
3
) exposure
group, and a minimal to mild degree of fibrosis was noted in 22% of the animals in the middle
(4mg/m
(4mg/m
3
) exposure group, but no pulmonary change was reported in the lowest (1mg/m
3
)
exposure group, the most relevant level to potential human exposures.
12.ECOLOGICAL INFORMATION
Ecotoxicity
On available data, toner is not harmful to aquatic organisms
13.DISPOSAL CONSIDERATIONS
Waste from Residues
: Waste material may be dumped or incinerated under conditions which meet all federal,
state and local environmental regulations.
Contaminated Packaging : Waste may be disposed or incinerated under conditions which meet all federal, state
and local environmental regulations.
14.TRANSPORT INFORMATION
UN Classification
: None
Not classified as hazardous for transport.
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